The Pharmacokinetic Characteristics of Sildenail Citrate Chewable Tablets Compared to Film-Coated Tablets in Healthy Male Subjects

But be careful about accidentally doubling up on doses.

Missing a dose before sex is no big deal, though doing so may impact the quality of your erection.

Choosing Between the Two

And, as is the case with taking any medication, following a professional’s medical advice is crucial. Unlike some other ED meds, you don’t take sildenafil every day. Sildenafil is an as-needed medication that should be taken at least about 30 minutes to an hour before sexual activity, and its effects should last up to four hours. You should never take more than one dose per day. You may be prescribed sildenafil or Viagra if you struggle with the following symptoms: Getting erections that aren't as firm as you'd like them to be Getting erections that aren't as firm as you'd like them to be Some medications can upset your stomach if you don’t take them with food.

THERAPEUTIC INDICATIONS:

You can take this ED medication with or without food. However, high-fat meals can impact the absorption of sildenafil, leading to lower peak plasma levels of the medication, which can translate to lower efficacy. Grapefruit juice can also interfere with how the body processes sildenafil, leading to more side effects. So, if you’re a half-grapefruit in the a.m. kind of guy, mention that to your healthcare provider before filling a sildenafil prescription. However, forgetting you already took sildenafil and taking a subsequent dose within 24 hours can lead to complications, particularly if you go over 100 milligrams total.

You should be aware of the potential side effects when taking any new drug. The most common side effects of sildenafil include: Most of these mild side effects will go away on their own as your body adapts to taking sildenafil.

Chewable Tadalafil

Their chemical composition sildenafil citrate tablets 50 mg could be altered, making them unsafe to consume. How can you tell if your medications are expired? Check the label for a date, likely next to the abbreviation “Exp.” Want more tips on how to get the most out of sildenafil? Read our guide on how to use Viagra for best results. It doesn’t really matter if you forget to take sildenafil because it’s designed for you to take it as you need it. But sildenafil also comes with some more rare but potentially serious side effects like: Sudden loss of vision (potentially a sign of non-arteritic anterior ischemic optic neuropathy or NAION) Sudden loss of vision (potentially a sign of non-arteritic anterior ischemic optic neuropathy or NAION) Priapism (a painful erection lasting longer than four hours) Priapism (a painful erection lasting longer than four hours) If you experience any of these symptoms after taking sildenafil, seek immediate medical attention.

Sildenafil Citrate Chewable Tablets USP 50mg Technical Specification:

You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510. If your healthcare provider just prescribed sildenafil citrate (generic Viagra®) to treat your erectile dysfunction (ED) symptoms, you’re probably excited to get your mojo back. But it’s also understandable if your head is swimming with questions.

CAUTION & WARNING:

Like other PDE5 inhibitors, or phosphodiesterase type 5 inhibitors, sildenafil is a safe treatment for ED, if used as directed. It’s been Food and Drug Administration (FDA)-approved for this use since 1998, after all. In an effort to provide some answers to your lingering questions, this guide will explain how to take sildenafil for the best results, a typical starting dosage, and potential side effects to consider. But remember that you should always follow your provider’s instructions for taking sildenafil—or any medication, for that matter. Sildenafil belongs to a class of drugs known as PDE5 inhibitors. And FYI: Even mild side effects can impact your life. If you get an upset stomach every time you take sildenafil, talk with a healthcare professional. They may recommend changing your dose or switching medications altogether. Read more about potential sildenafil reactions in our sildenafil side effects guide.

• Sildenafil tablets are not a cure for erectile dysfunction but help achieve an erection.
• Take the tablet 15-20 minutes before sexual activity for best results.
• Avoid grapefruit or grapefruit juice while using sildenafil.

It might be dangerous to use sildenafil if you have certain medical conditions or take specific drugs.

• Chewable sildenafil can be purchased in various flavors to improve taste.
• They are often more discreet and easier to carry than traditional tablets.
• Proper disposal of unused medication is crucial to prevent misuse.

If your healthcare provider told you not to engage in sexual activity because of a heart condition (like a history of heart attack; heart disease; heart failure; angina; or arrhythmia, also known as an irregular heartbeat), it’s probably best to abstain from having sex and taking sildenafil. Using sildenafil when you take medicines for high blood pressure or pulmonary arterial hypertension could cause a dangerous, potentially life-threatening dip in blood pressure.

Shipping Information

In the corpus cavernosum, this leads to penile erection. In the pulmonary system, it leads to vasodilation in the pulmonary arteries. Oxytocin may possess antidiuretic effects—extended administration may increase risk of fluid overload Cardiovascular disease, due to oxytocin’s potential vasopressor effects Known hypersensitivity to sildenafil or tablet excipients Use of nitrates and alpha-blockers due to risk of life-threatening hypotension Severe hepatic impairment (Child-Pugh Class C) Severe renal impairment (creatinine clearance <30 mL/min) History of NAION (non-arteritic anterior ischemic optic neuropathy) Store at controlled room temperature (20°C to 25°C / 68°F to 77°F) Osilla EV, Patel P, Sharma S. Oxytocin. This information is for educational purposes only.

Stop taking medication for ED if you notice any concerning symptoms

This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition. It may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. Avoid taking sildenafil with nitrates (medications for chest pain) such as isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, and alpha-blockers or other blood pressure medications like riociguat.

• The recommended dose varies, typically 50 mg, but consult a healthcare professional.
• Chewable sildenafil enhances onset speed compared to standard tablets.
• Avoid alcohol while using sildenafil to reduce the risk of adverse effects.

If you have a condition that puts you at higher risk of priapism—like sickle cell anemia, leukemia, Peyronie’s disease, or multiple myeloma—you should avoid sildenafil. There isn’t enough data to say whether sildenafil is safe for people with this eye condition.

Sildenafil can interact with the nitrites found in certain recreational drugs popularly known as “poppers,” causing a dangerous drop in blood pressure. Don’t mix sildenafil with other ED drugs, like Cialis®, Levitra®, Revatio® (another brand name for sildenafil) or Stendra®.

At a glance

Keep sildenafil out of the reach of children and pets, and store the medication at room temperature between 68°F to 77°F (20°C to 25°C). You should always follow your doctor’s instructions regarding sildenafil dosing, but your total daily dosage should never exceed 100 milligrams. Even if you’re not getting results from a 100-milligram dose of sildenafil, don’t try to take more. If sildenafil isn’t helping with your lackluster erections, there are a few possible reasons. Another kind of treatment altogether (like therapy for psychological ED) Another kind of treatment altogether (like therapy for psychological ED) Addressing underlying health conditions that can contribute to ED Addressing underlying health conditions that can contribute to ED Additionally, taking sildenafil too early (we’re talking more than a few hours before having sex) won’t produce the effects you’re looking for.

QUALITATIVE AND QUANTITATIVE COMPOSITION:

That means you have to do a bit of sex planning when taking sildenafil. But you might be surprised at how sexy the anticipation can be—for you and your partner. Spend that time exploring new foreplay ideas or sharing your sexual fantasies. Avoid taking sildenafil if it’s expired. According to the FDA, you should skip taking any expired meds and safely dispose of them for the following reasons: Their chemical composition could be altered, making them unsafe to consume. This can put you at risk for low blood pressure. More of something isn’t always better! Aside from heart medications and other PDE5 inhibitors, taking sildenafil with ritonavir, ketoconazole, itraconazole, or clarithromycin (an antibiotic) can increase the concentration of sildenafil in your body and make you more likely to experience side effects. Talk with a healthcare professional before mixing sildenafil with over-the-counter supplements, which aren’t regulated in the same way as prescription drugs.

Learn more about health and drug interactions in our sildenafil interactions guide. If you’re living with ED symptoms, you’re not alone. Sildenafil can make it easier to get and keep an erection so you can enjoy a fulfilling sex life.

About the Company

These medications block the PDE5 enzyme, resulting in the widening of your blood vessels to promote blood flow to the penis. This increased blood flow results in an erection. However, sildenafil doesn’t affect your libido. You still need to be aroused to get and maintain an erection long enough to yield satisfying sex. Healthcare providers can prescribe sildenafil tablets in different doses.

Potential side effects of tadalafil

A typical starting dose of sildenafil is 50 milligrams, which you’d take 30 minutes to four hours before sexual activity. Your provider may adjust your dosage depending on your needs and how you respond to the medication. It’s also possible you may get a prescription in doses that are multiples of 20 milligrams, including 20 milligrams, 40 milligrams, 60 milligrams, and 80 milligrams. In these cases, your sildenafil tablets would actually be the generic form of Revatio®, a medication that has the ingredient sildenafil, like Viagra, but is FDA-approved for pulmonary arterial hypertension (although it can be prescribed off-label for ED). Be sure to talk through all options with your healthcare provider. Here’s what to remember when taking sildenafil for ED: Take it at least 30 to 60 minutes and no more than four hours before sexual stimulation. Also, avoid high-fat foods or meals that can slow absorption.

• Patients with liver or kidney problems should inform their doctor before use.
• Sildenafil may cause a temporary drop in blood pressure.
• Regular check-ups are recommended for those on long-term medication.

Take it at least 30 to 60 minutes and no more than four hours before sexual stimulation.